Anxiety And Depression Problems in Women Having Ovarian Germ Cell and Sex Cord Stromal Tumors

Abstract

Gynaecological cancers are relatively frequent in the female population. Malignant sex cord-stromal tumours are rare and include granulosa cell tumours (most common) and Sertoli-Leydig cell tumours; they are typically associated with a good prognosis. Most of the patients with granulosa tumours present with early-stage disease. The disease is typically indolent. Patients with stage IA or IC sex cord-stromal tumours desiring to preserve their fertility should be treated with fertility-sparing surgery.  The standard treatment mainly involves conservative surgery combined with chemotherapy depending on the stage and the prognostic factors, as for testicular cancers. As reported in testicular cancer survivors, chemotherapy may induce sequelae impacting quality of life, which has not yet been evaluated in survivors of germ cell tumors and sex cord stromal tumors.